An integrated approach to skin sparing mastectomy with tissue expander placement followed by radiotherapy and delayed reconstruction was initiated in our institution in 2002. The purpose of this study was to assess the surgical outcomes of this strategy.Between September 2002 and August 2013, a total of 384 reconstructions had a tissue expander placed at the time of mastectomy and subsequently underwent radiotherapy. Rates and causes of tissue expander explantation before, during, and after radiotherapy, as well as tumor specific outcomes and reconstruction approaches, were collected.Median follow-up after diagnosis was 5.6 (range 1.3-13.4) years. In the study cohort, 364 patients (94.8

作者：Zeina, Ayoub；Eric A, Strom；Valentina, Ovalle；George H, Perkins；Wendy A, Woodward；Welela, Tereffe；Benjamin D, Smith；Simona F, Shaitelman；Michael C, Stauder；Karen E, Hoffman；Sarah M, DeSnyder；Patrick B, Garvey；Mark W, Clemens；Carlos H, Barcenas；Henry M, Kuerer；Steven, Kronowitz

来源：Annals of surgical oncology 2017 年