The relationship between cervical cancer and the use of depot-medroxyprogesterone acetate (DMPA) was examined in a nationwide case-control study in Costa Rica. Cases were women ages 25-58 years of age with invasive squamous cell cancer (N = 149) or carcinoma in situ (CIS, N = 415) reported by the National Tumor Registry during 1982-84. Controls (N = 764) were randomly selected during a nationwide household survey. Using logistic regression, we adjusted for known risk factors for cervical cancer. DMPA use was associated with a risk of CIS of 1.1 (95
作者:M W, Oberle;L, Rosero-Bixby;K L, Irwin;J A, Fortney;N C, Lee;A S, Whatley;M G, Bonhomme
来源:International journal of epidemiology 1988 年 17卷 4期