目的:初步探讨腹水CEA/血清CEA、腹水CA19-9/血清CA19-9、腹水CA125/血清CA125、血清CEA、血清CA19-9和血清CA125对腹膜假黏液瘤的诊断价值.方法:研究对象包括102例经病理确诊的腹膜假黏液瘤患者,46例由腹部其他疾病产生腹水的患者,作为疾病对照组.应用化学发光法测定上述两组腹水和血清的CEA、CA19-9和CA125,分析两组上述肿瘤标志物的差异有无统计学意义.进一步把腹膜假黏液瘤组分为高级别组(n=35)和低级别组(n=67),比较组间肿瘤标志物水平,P＜0.05认为差异有统计学意义.结果:腹膜假黏液瘤病例组和疾病对照组中腹水CEA/血清CEA、腹水CA19-9/血清CA19-9、腹水CA125/血清CA125、血清CEA、血清CA19-9、血清CA125水平分别为[115.05(41.99,292.25)vs.0.60(0.25,2.25),Z=-8.502,P=O.001]、[14.23(4.33,37.67)vs.1(0.50,1.72),Z=-7.030,P=0.001]、[7.38(3.64,11.92)vs.2.26(1.36,4.37),Z=-5.309,P =0.001]、[39.75(11.70,114.89)vs.3.54(1.44,6.53),Z=-6.869,P=0.001]、[84.72(22.39,420.93)vs.12.71(2.45,65.24),Z=-3.749,P =0.001]、[64.40(29.85,142.85)vs.379.75(151.88,620.02),Z=-6.463,P=0.001],病例组中腹水CEA/血清CEA、腹水CA19-9/血清CA19-9、腹水CA125/血清CA125、血清CEA、血清CA19-9的水平比对照

作者：马福存；柏明见；何美琳；卢一艳；梁国威；宋燕

来源：标记免疫分析与临床 2019 年 26卷 5期