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Objective This study was to determine the antimicrobial susceptibility of P acnes in acne patients in Guangzhou city of southern China.Methods Among 124 patients,we isolated 100 stains of P.acnes and did the antimicrobial susceptibility tests in vitro.Results By applying the Clinical and Laboratory Standards Institute document M 1 l-A7 breakpoints for resistance,11%,39%,36%,71%,72%,53%,3%,28% of the stains were resistant to minocycline,doxycycline,tetracycline,erythromycin,azithromycin,clindamycin,ceftriaxone and levofloxacin,respectively.Moreover,severe cross/multiple resistance was also observed.Conclusion The high prevalence of antimicrobial resistant P.acnes should cause alarm and attention in Guangzhou.

来源:国际皮肤性病学杂志 2018 年 1卷 1期

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来源:
国际皮肤性病学杂志 2018 年 1卷 1期
标签:
Propionibacterium acnes Acne vulgaris Microbial sensitivity test Drug resistance
Objective This study was to determine the antimicrobial susceptibility of P acnes in acne patients in Guangzhou city of southern China.Methods Among 124 patients,we isolated 100 stains of P.acnes and did the antimicrobial susceptibility tests in vitro.Results By applying the Clinical and Laboratory Standards Institute document M 1 l-A7 breakpoints for resistance,11%,39%,36%,71%,72%,53%,3%,28% of the stains were resistant to minocycline,doxycycline,tetracycline,erythromycin,azithromycin,clindamycin,ceftriaxone and levofloxacin,respectively.Moreover,severe cross/multiple resistance was also observed.Conclusion The high prevalence of antimicrobial resistant P.acnes should cause alarm and attention in Guangzhou.