Objective: To investigate the expression of stathmin in eutopic endometrium of women with or without endometriosis.Methods: The eutopic endometrium samples were collected from thirty-six women with endometriosis and nineteen age-matched women without endometriosis. The expression of stathmin protein was detected by immunohisto-chemistry and Western blot.Results: Stathmin was expressed in both endometrial glandular and stromal cells throughout the menstrual cycle. Stathmin expression had no significant difference between proliferative and secretory phase. Stathmin was overexpressed in eutopic endometrium of women with endometriosis compared with those without endometriosis.Conclusion: The overexpressed stathmin in endometrium of patient with endometriosis may play a certain role in the pathogenesis of endometriosis.

来源：生殖医学杂志 2009 年 18卷 z2期