objective　Based on the Guidelines for Surveillance of Drug Resistance in Tuberculosis of WHO/IUATLD set up a system for surveillance of drug resistance of pulmonary tuberculosis.To obtain the result on initial and acquired drug resistance rate of pulmonary tuberculosis in Guangdong province of China.Methods　40 counties were selected randomly in 113 counties of Guangdong province.39 cases of the new smear positive of pulmonary tuberculosis were intaken continuously in every county,including retreatment smear positive,Identify type of strains of culture positive and test drug resistance of the four kinds of antituberulosis drugs.Result　Total drug resistance rate is 19.6

作者：钟球；钱明；李建伟；陈启亮；卓文基；江勇；黄树智；陈燕梅

来源：中国防痨杂志 2001 年 23卷 1期