Platelet concentrate ( PC ) for surgical use is an evolution of the fibrin glue technologies used since many years. The initial concept of these preparations was to concentrate platelets and their growth factors and activate it into a fibrin gel on a surgical site, in order to improve local healing. The platelets contain alpha granules that are rich in several growth factors, such as platelet-derived growth factor, vascular endothelial growth factor, transforming growth factor-β, insulin-like growth factor, and epidermal growth factor, which play the essential roles in tissue healing and regeneration mechanisms. The relative ease of obtaining and preparation, convenience and applicability in the clinical setting, favorable safety profile and possible beneficial outcomes make PCs a new promising therapeutic approach for future regenerative therapy strategy. Numerous techniques of PC have been developed. The most common forms of autologous platelet concentrates: Platelet rich plasma ( PRP ) and platelet ri

作者：李晋；王文波；谢燕霞；阎影

来源：中国骨与关节杂志 2013 年 7期