Objective To investigate the clinicopathologic features and main points of diagnosis and differential diagnosis of Charcot's joint.Methods A case of Charcot's joint was studied and the related literatures were reviewed.Its clinical manifestations and pathomorphological characteristics were analyzed.Results A 41-year-old male was admitted to the hospital due to loss of range of motion ( ROM ) of the left shoulder joint progressively and painlessly.The X-ray showed the humeral head was partially missing.The CT represent ed irregular soft tissue mass es in high density with an indistinct edge,and discontiguous left scapulabone.The MRI showed changes of syringomyelia was presented in the glenoid cavity of the left shoulder joint,humeral head,proximal humerus and spinal cord of thoracic segments.According to the histological ifndings,free bone detritus accumulationswere microscopicallyseen in the lesions and adjacent soft tissues at an early stage,andthe secondary changes due to the reactions of osteoclast-likem

作者：李灿；孙娟娟；王朝夫

来源：中国骨与关节杂志 2015 年 4卷 5期