In vivo experiments performed on rats show marked decrease in intestinal glucose absorption following burn injury. Glucose absorption is partially increased by insulin administration (0.001 U/100g body weight). There was a linear relationship between blood sugar levels and the rate of glucose absorption. One week after scalding blood serum insulin was decreased and blood glucose levels were highly increased, showing that stress diabetes mellitus tends to appear. In order to avoid the complications involved in in vivo experiments, some rats were rendered diabetic by alloxan administration and their rate of glucose absorption was greatly decreased in vivo. However, in vitro measurement of intestinal glucose absorption revealed no marked difference between normal and diabetic rats. Insulin control is not primarily due to the active transport system for glucose but is probably secondary to changes in blood sugar levels.

作者：Qin Zheng-yu；Xu Ai-hua

来源：CHINESE MEDICAL JOURNAL 1987 年 100卷 4期