Background::Minimal change nephropathy (MCD) is a common pathological type of nephrotic syndrome and is often associated with acute kidney injury (AKI). This study aimed to investigate the clinical characteristics and related factors of AKI in patients with MCD and nephrotic syndrome.Methods::Patients from Chinese People’s Liberation Army General Hospital who were diagnosed with pathological renal MCD with clinical manifestations of nephrotic syndrome were included from January 1, 2013 to December 31, 2017. Patients diagnosed with membranous nephropathy (MN) by renal biopsy from January 1, 2013 to December 31, 2017 are included as a control population. We retrospectively analyzed the clinical and pathological characteristics of patients as well as the percentages and clinical characteristics of AKI in different age groups. We assessed the correlation of pathological characteristics with serum creatinine using multivariate linear regression analysis.Results::A total of 367 patients with MCD were included in t

作者：Lin Shu-Peng；Zhu Feng-Ge；Meng Jin-Ling；Sun Xiao-Wei；Cui Jing；Liang Shuang；Yin Zhong；Sun Xue-Feng；Cai Guang-Yan

来源：中华医学杂志英文版 2021 年 134卷 2期