Background:Endometrial cancer (EC) has been one of the most general cancers with respect to gynecological malignancies; however, there are debates on clinical strategies concerning treatments especially for patients with grade 3 (G3) endometroid endometrial cancer (EEC). Present study aimed to evaluate the lymphatic metastasis (LM) related factors and figure out the necessity of lymphadenectomy for G3 EEC patients.Methods:From January 2009 to April 2019, 3751 EC patients were admitted to Obstetrics and Gynecology Hospital of Fudan University. Clinical characteristics include age, grade, stage, and clinical pathological features. A total of 1235 EEC patients were involved in the multivariable analysis. Three hundred and eighty-one patients were involved in the survival analysis and the data attributed to sufficient follow-up information. Kaplan-Meier curve and log-rank test were utilized to analyze the survival rate.Results:Among the 1235 EEC patients, 181 (14.7

作者：Wang Bo；Wang Qian；Shi Yue；Shao Wen-Yu；Liao Jiong-Bo；Luo Xue-Zhen；Chen Xiao-Jun；Wang Chao

来源：中华医学杂志英文版 2021 年 134卷 17期