Objective::Cardiovascular diseases are associated with an increased risk of depression, but it remains unclear whether treatment with cardiovascular agents decreases or increases this risk. The effects of drugs on individual usage are also often unknown. This review aimed to examine the correlation between depression and common cardiovascular drugs, develop more potent interventions for depression in cardiovascular patients, and further research on the bio-behavioural mechanisms linking cardiovascular drugs to depression.Data sources::The data in this review were obtained from articles included in PubMed, EMBASE, and Web of Science.Study selection::Clinical trials, observational studies, review literature, and guidelines about depression and cardiovascular drugs were selected for the article.Results::We systematically investigated whether the seven most used cardiovascular drugs were associated with altered risk of incident depression in this literature review. Statins have been proven to have antidepressant

作者：Shu-Hui Tao；Xue-Qun Ren；Li-Jun Zhang；Mei-Yan Liu

来源：中华医学杂志英文版 2021 年 134卷 22期