Purpose:To compare the local control rate and side effects of external radiation combined with brachytherapy and external radiation alone for early nasopharyngeal carcinoma (NPC).Materials and Methods:A total of 124 patients with T
1, T
2 NPC was evaluated in this study between March 1990 and November 1996. The median follow-up periods were 62 months with 5 cases lost. There were male 86, female 38. The ages ranged from 16~70 yrs. Poorly differentiated squamous cell carcinoma except 1 adeno-squamous cell carcinoma were proved by histopathology at the primary sites. The external radiation was given by 6~8 MV X-rays and
192 Ir was used for intracavitary brachytherapy. The patients treated by RT alone group received a total dose of 70~86 Gy in 7~9 weeks and that of RB group was 50~70Gy in 5~7 weeks. The dose of brachytherapy ranged 8~24 Gy in 1~3 fractions in 1~3 weeks. Kaplan-Meier and log-rank test were used for evaluating the results of the local control and survival rates in this series.
作者:Gao Li;Xu Guozhen;Xiao Guangli
来源: 1997 年 06卷 4期