Objective To analyze and summarize the clinical characteristics,diagnosis and treatment of necrotizing sarcoid granulomatosis(NSG).Methods A description of an elderly patient with NSG who was diagnosed through biopsy and received treatment at Beijing Hospital and a review of the literature on 73 NSG cases reported in China and elsewhere.Results The patient was a 60-year-old woman presenting with fever,cough and chest pain.Chest CT scan showed multiple miliary nodules without mediastinal adenopathy.A biopsy specimen was taken via thoracoscopy and a diagnosis of NSG was confirmed microscopically.The patient was not given any medication and experienced spontaneous remission.An analysis of a total of 74 NSG cases(including this one and 73 others from literature)shows that 22 of the patients were male and 52 female,aged from 8 to 77 years.Of all the cases,62 involved the lungs alone,while the rest implicated extrapulmonary tissues.The most common complaints were cough(37 cases or 50.0%),fever(28 cases or 37.8%
作者:居阳;李燕明;方芳;柯会星;孙铁英
来源:中华老年医学杂志 2016 年 35卷 11期