Different from the previous knowledge regarding reactive oxygen species (ROS),recent research suggests that ROS play essential roles in initiating cascade reaction of wound healing.During wound healing,ROS can serve as the second messenger to regulate signal transduction and gene expression.In this paper,we review the mechanism of generation of cyclooxygenase 2-prostaglandin E2 induced by ROS,which regulates the early inflammatory response and subsequent healing after injury.
作者：胡逸萍；张一帆；张云松；姚敏
来源：中华烧伤杂志 2014 年 30卷 3期
