Background::Ventilator-associated pneumonia (VAP) represents a common hospital-acquired infection among mechanically ventilated patients. We summarized evidence concerning ventilator care bundles to prevent VAP.Methods::A systematic review and meta-analysis were performed. Randomized controlled trials and controlled observational studies of adults undergoing mechanical ventilation (MV) for at least 48 h were considered for inclusion. Outcomes of interest were the number of VAP episodes, duration of MV, hospital and intensive care unit (ICU) length of stay, and mortality. A systematic search was conducted in the MEDLINE, the Cochrane Library, and the Web of Science between 1985 and 2022. Results are reported as odds ratio (OR) or mean difference (MD) with 95

作者：Martinez-Reviejo Raquel；Tejada Sofia；Jansson Miia；Ruiz-Spinelli Alfonsina；Ramirez-Estrada Sergio；Ege Duygu；Vieceli Tarsila；Maertens Bert；Blot Stijn；Rello Jordi

来源：重症医学（英文） 2023 年 03卷 4期