Polymorphisms within the P1 isoenzyme of GST (GSTP1) are associated with alterations in enzyme activity and may change sensitivity to platinum-based chemotherapy. We investigated the rela...
来源:《Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer》 2006 年 1卷 7期
The genes encoding the enzymes for metabolising alcohol dehydrogenase 1B (ADH1B) and aldehyde dehydrogenase 2 (ALDH2) - exhibit genetic polymorphism and ethnic variations. Although the AL...
It has been suggested in a number of studies that susceptibility to adult Hodgkin's disease (HD) is influenced by the HLA class II region, and specifically by alleles at the HLA-DPB1 locu...
To investigate associations between HLA-DQB1*0602 allele status and measures of narcolepsy symptom severity.Cross-sectional study of population-based narcolepsy patients.King County, Wash...
We studied the dynamics of Aβ40 , involved in Alzheimer's disease, by using 21 methods combined from Amber03, Amber99sb-ILDN, Charmm27, Charmm22*, OPLS-2001, OPLS-2006, OPLS-2008, Gromos...
来源:《Chemphyschem : a European journal of chemical physics and physical chemistry》 2015 年 16卷 15期