We report a case of an 86-year-old woman admitted to the hospital with rhabdomyolysis and acute kidney injury 3 weeks after starting sitagliptin while on long-term atorvastatin therapy. She also had low levels of 25-hydroxyvitamin D and mild chronic kidney disease, which may have contributed to the development of rhabdomyolysis. A review of the literature reveals four previous reports of this drug interaction in elderly patients, some with underlying kidney disease.
作者:Rupinder Singh, Buttar;Jasveen, Batra;Jacqueline, Kreimerman;Melissa, Aleta;Michal L, Melamed
来源:Journal of general internal medicine 2017 年