Background::Extreme temperature events, including extreme cold, are becoming more frequent worldwide, which might be harmful to pregnant women and cause adverse birth outcomes. We aimed to investigate the association between exposure to low ambient temperature in pregnant women and adverse birth outcomes, such as preterm birth, low birth weight, and stillbirth, and to summarize the evidence herein.Methods::Relevant studies were searched in PubMed, Cochrane, and Embase electronic databases until November 2021. Studies involving low ambient temperature, preterm birth, birth weight, and stillbirth were included. The guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-analyses were followed to conduct this study risk of bias and methods for data synthesis.Results::A total of 34 studies were included. First, pregnant women exposed to low ambient temperature had an increased risk of preterm birth (risk ratio [RR] 1.08; 95

作者：Ruan Tiechao；Yue Yan；Lu Wenting；Zhou Ruixi；Xiong Tao；Jiang Yin；Ying Junjie；Tang Jun；Shi Jing；Wang Hua；Xiao Guoguang；Li Jinhui；Qu Yi；Mu Dezhi

来源：中华医学杂志英文版 2023 年 136卷 19期