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Patients with schizophrenia or bipolar disorder (BPD) may be differentially sensitive to antipsychotics. This study assessed the median time to onset, duration, and rate of somnolence associated with asenapine and other antipsychotics in both indications.Ten clinical trials (n = 4786) were analyzed as five cohorts pooled according to indication and study design.In the short-term schizophrenia cohort, the incidence of somnolence was 13.1

作者:Keming, Gao;Mary, Mackle;Pilar, Cazorla;Jun, Zhao;Armin, Szegedi

来源:Neuropsychiatric disease and treatment 2013 年 9卷

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作者:
Keming, Gao;Mary, Mackle;Pilar, Cazorla;Jun, Zhao;Armin, Szegedi
来源:
Neuropsychiatric disease and treatment 2013 年 9卷
标签:
asenapine bipolar disorder schizophrenia sedation somnolence
Patients with schizophrenia or bipolar disorder (BPD) may be differentially sensitive to antipsychotics. This study assessed the median time to onset, duration, and rate of somnolence associated with asenapine and other antipsychotics in both indications.Ten clinical trials (n = 4786) were analyzed as five cohorts pooled according to indication and study design.In the short-term schizophrenia cohort, the incidence of somnolence was 13.1