Uncorrected serum calcium concentration is the first mineral metabolism metric planned for use as a quality measure in the United States ESRD population. Few studies in patients undergoing either peritoneal dialysis (PD) or hemodialysis (HD) have assessed the association of uncorrected serum calcium concentration with clinical outcomes. We obtained data from 129,076 patients on dialysis (PD, 10,066; HD, 119,010) treated in DaVita, Inc. facilities between July 1, 2001, and June 30, 2006. After adjustment for potential confounders, uncorrected serum calcium <8.5 and ≥10.2 mg/dl were associated with excess mortality in patients on PD or HD (comparison group uncorrected calcium 9.0 to <9.5 mg/dl). Additional adjustment for serum albumin concentration substantially attenuated the all-cause mortality hazard ratios (HRs) associated with uncorrected calcium <8.5 mg/dl (HR, 1.29; 95

作者：Matthew B, Rivara；Vanessa, Ravel；Kamyar, Kalantar-Zadeh；Elani, Streja；Wei Ling, Lau；Allen R, Nissenson；Bryan, Kestenbaum；Ian H, de Boer；Jonathan, Himmelfarb；Rajnish, Mehrotra

来源：Journal of the American Society of Nephrology : JASN 2015 年 26卷 7期