To evaluate the effects of discontinuing chronic beta-blocker (BB) treatment on short-term outcome in patients with chronic heart failure (CHF) during acute decompensation.We selected all the patients previously diagnosed with CHF and currently on BB and attended for acute heart failure (AHF) in one of the 35 Spanish emergency departments participating in the EAHFE registry. Patients were classified according to BB maintenance or withdrawal (BBM or BBW, respectively) during the episode. In-hospital mortality was the primary endpoint; and 30-day mortality, 30-day combined endpoint, and prolonged hospitalization were secondary. We used logistic regression for adjustment of results according to the differences between the BBM and BBW groups, and stratified analysis by age, sex, left ventricular ejection fraction, chronic obstructive pulmonary disease, heart rate (HR), and BB type (carvedilol/bisoprolol) was performed.Among 2058 patients receiving chronic BB treatment, 1990 were analyzed: BBM 530 (27 

作者：òscar, Miró；Christian, Müller；Francisco Javier, Martín-Sánchez；Héctor, Bueno；Alexander, Mebazaa；Pablo, Herrero；Javier, Jacob；Víctor, Gil；Rosa, Escoda；Pere, Llorens

来源：Clinical research in cardiology : official journal of the German Cardiac Society 2016 年 105卷 12期