Genetic variation in the clusterin gene has been associated with Alzheimer Disease (AD), and the clusterin protein is thought to play a mechanistic role. We explored the associations of clusterin plasma levels with incident dementia, AD, and stroke.Plasma clusterin was assessed in 1532 nondemented participants from the Framingham Study Offspring cohort between 1998 and 2001 (mean age, 69 ± 6; 53
作者:Galit, Weinstein;Alexa S, Beiser;Sarah R, Preis;Paul, Courchesne;Vincent, Chouraki;Daniel, Levy;Sudha, Seshadri
来源:Alzheimer's & dementia (Amsterdam, Netherlands) 2016 年 3卷