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Aging of persons with human immunodeficiency virus (HIV) resulted in high rates of osteopenia and osteoporosis. Multiple cohort studies have reported an increased prevalence of bone demineralization among HIV-infected individuals. The aim of this study was to evaluate bone mineral density (BMD) and risk factors for osteopenia/osteoporosis among HIV-positive patients attending the National Institute for Infectious Diseases "Prof.Dr. Matei Balș", Bucharest, Romania.We performed a cross-sectional study that enrolled 60 patients with HIV. The association between BMD and lifestyle habits (smoking), body mass index (BMI), nadir cluster of differentiation 4 (CD4) cell count, current CD4 cell count, HIV viral load and history of combination antiretroviral therapy (cART) were investigated. The BMD was measured at the lumbar spine, hips and total body using dual-energy X-ray absorptiometry (DEXA).In the present study, DEXA evaluation showed an overall prevalence of osteoporosis of 16.66

作者:Cristina-Emilia, Chi?u-Ti?u;Ecaterina-Constan?a, Barbu;Mihai, Laz?r;Daniela Adriana, Ion;Ioana Anca, B?d?r?u

来源:Germs 2016 年 6卷 2期

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| 浏览:41
作者:
Cristina-Emilia, Chi?u-Ti?u;Ecaterina-Constan?a, Barbu;Mihai, Laz?r;Daniela Adriana, Ion;Ioana Anca, B?d?r?u
来源:
Germs 2016 年 6卷 2期
标签:
HIV antiretroviral therapy bone mineral density osteopenia osteoporosis
Aging of persons with human immunodeficiency virus (HIV) resulted in high rates of osteopenia and osteoporosis. Multiple cohort studies have reported an increased prevalence of bone demineralization among HIV-infected individuals. The aim of this study was to evaluate bone mineral density (BMD) and risk factors for osteopenia/osteoporosis among HIV-positive patients attending the National Institute for Infectious Diseases "Prof.Dr. Matei Balș", Bucharest, Romania.We performed a cross-sectional study that enrolled 60 patients with HIV. The association between BMD and lifestyle habits (smoking), body mass index (BMI), nadir cluster of differentiation 4 (CD4) cell count, current CD4 cell count, HIV viral load and history of combination antiretroviral therapy (cART) were investigated. The BMD was measured at the lumbar spine, hips and total body using dual-energy X-ray absorptiometry (DEXA).In the present study, DEXA evaluation showed an overall prevalence of osteoporosis of 16.66