Sustained glycaemic control and less nocturnal hypoglycaemia with insulin glargine 300U/mL compared with glargine 100U/mL in Japanese adults with type 1 diabetes (EDITION JP 1 randomised 12-month trial including 6-month extension).-临床诊疗知识库

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To evaluate the efficacy and safety of insulin glargine 300U/mL (Gla-300) versus glargine 100U/mL (Gla-100) in adults with type 1 diabetes in Japan over 12months.EDITION JP 1 was a multicentre, randomised, open-label phase 3 study. Following a 6-month on-treatment period, participants continued to receive Gla-300 or Gla-100 once daily, plus mealtime insulin, over a 6-month open-label extension phase. HbA1c, hypoglycaemia, body weight and adverse events were assessed.Overall, 114/122 (93

作者：Munehide, Matsuhisa；Masayoshi, Koyama；Xi, Cheng；Mariko, Sumi；Matthew C, Riddle；Geremia B, Bolli；Takahisa, Hirose

来源：Diabetes research and clinical practice 2016 年 122卷

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