Cerebral microbleeds and risk of incident dementia: the Framingham Heart Study.-临床诊疗知识库

Cerebral microbleeds and risk of incident dementia: the Framingham Heart Study.

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作者：

José R, Romero；Alexa, Beiser；Jayandra J, Himali；Ashkan, Shoamanesh；Charles, DeCarli；Sudha, Seshadri

来源：

Neurobiology of aging 2017 年 54卷

标签：

Brain MRI Cerebral microbleeds Cerebral small vessel disease Dementia

Cerebral microbleeds (CMBs) are MRI markers attributed to the most common cerebral angiopathies in the elderly and in patients with dementia: hypertensive and cerebral amyloid angiopathy. CMB detection in asymptomatic persons may help identify those at risk for dementia and may influence preventive strategies and design of clinical trials testing treatments for dementia. We studied the association of CMB with risk of incident dementia in community dwelling individuals. A total of 1296 dementia-free Framingham Heart Study participants (mean age 72 years; 54

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