We evaluated the clinical course of patients prenatally diagnosed and enrolled early with congenital solitary functioning kidney, and identified the risk factors for renal injury.We retrospectively evaluated 322 patients with congenital solitary functioning kidney according to the inclusion criteria of 1) prenatal diagnosis of solitary kidney; 2) first evaluation at 1 to 3 months of life with confirmation of congenital solitary functioning kidney and evaluation of possible associated congenital anomalies of the kidney and urinary tract by abdominal ultrasound, renal scintigraphy and cystography; and 3) absence of any condition potentially affecting renal function in the neonatal period as well as absence of renal injury at enrollment (1 to 3 months of life) confirmed by a normal estimated glomerular filtration rate, lack of proteinuria and hypertension. Followup of 306 patients was evaluated.Median followup was 7.2 years (range 1 to 23) and 1 or more signs of renal injury were found in 12 of 306 patients (3.9

作者：Pierluigi, Marzuillo；Stefano, Guarino；Anna, Grandone；Allegra, Di Somma；Nicoletta, Della Vecchia；Tiziana, Esposito；Giulia, Macchini；Rosaria, Marotta；Andrea, Apicella；Mario, Diplomatico；Pier Francesco, Rambaldi；Laura, Perrone；Emanuele, Miraglia Del Giudice；Angela, La Manna；Cesare, Polito

来源：The Journal of urology 2017 年