BACKGROUND: Literatures have reported that the density changes of dopamine transporter is negatively correlated with the severity degree and grading of disease condition of Parkinson disease (PD). However, the distribution of dopamine transporter in each nucleus of corpora striatum at each period is still unclear.OBJECTIVE: To observe the radioactive uptake distribution of dopamine transporter in bilateral corpora striata of patients with different stages of PD using single photon emission computed tomography (SPECT),and make a comparison with healthy controls.DESIGN: Case-control analysis.SETTING: Department of Imageology, Second Hospital Affiliated to Guangzhou University of Chinese Medicine.PARTICIPANTS: Thirty patients with PD admitted to Second Hospital Affiliated to Guangzhou University of Traditional Chinese Medicine between January and December 2005 were recruited. The involved patients,19 male and 11 female, were aged from 36 to 80 years and with disease course of 2.5 months to 10 years.They all me

来源：中国神经再生研究（英文版） 2007 年 2卷 1期