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Background::The scale assessment was helpful in predicting the presence of antibodies to autoimmune encephalitis. This study aimed to evaluate the application of antibody prevalence in Chinese patients with epilepsy and encephalopathy (APE2-CHN) and response to immunotherapy in Chinese patients with epilepsy and encephalopathy (RITE2-CHN) for patients with different neuronal surface antibodies.Methods::A total of 1365 patients with epileptic seizures as the prominent feature in Xuanwu Hospital, Capital Medical University, from June 2016 to June 2020 were enrolled in our study. Of these, 915 patients with epilepsy of unknown etiology whose serum and/or cerebrospinal fluid samples were examined for autoimmune antibodies were selected. All patients were scored with antibody prevalence in patients with epilepsy and encephalopathy (APE2), response to immunotherapy with epilepsy and encephalopathy (RITE2), APE2-CHN, and RITE2-CHN scores.Results::Of the 915 patients, 191 patients were positive for neural-surface spe

作者:Yu Jia;Hui-Fang Wang;Meng-Yao Zhang;Yu-Ping Wang

来源:中华医学杂志英文版 2021 年 134卷 24期

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收藏
| 浏览:35 | 下载:2
作者:
Yu Jia;Hui-Fang Wang;Meng-Yao Zhang;Yu-Ping Wang
来源:
中华医学杂志英文版 2021 年 134卷 24期
标签:
APE2-CHN RITE2-CHN APE2 RITE2 Neuronal surface antibody Immunotherapy APE2-CHN RITE2-CHN APE2 RITE2 Neuronal surface antibody Immunotherapy
Background::The scale assessment was helpful in predicting the presence of antibodies to autoimmune encephalitis. This study aimed to evaluate the application of antibody prevalence in Chinese patients with epilepsy and encephalopathy (APE2-CHN) and response to immunotherapy in Chinese patients with epilepsy and encephalopathy (RITE2-CHN) for patients with different neuronal surface antibodies.Methods::A total of 1365 patients with epileptic seizures as the prominent feature in Xuanwu Hospital, Capital Medical University, from June 2016 to June 2020 were enrolled in our study. Of these, 915 patients with epilepsy of unknown etiology whose serum and/or cerebrospinal fluid samples were examined for autoimmune antibodies were selected. All patients were scored with antibody prevalence in patients with epilepsy and encephalopathy (APE2), response to immunotherapy with epilepsy and encephalopathy (RITE2), APE2-CHN, and RITE2-CHN scores.Results::Of the 915 patients, 191 patients were positive for neural-surface spe