Background::Female breast cancer (FBC) has become the most prevalent malignancy worldwide. We aimed to evaluate the global and regional burden in epidemiological trends and factors associated with the incidence and mortality of FBC.Methods::FBC incidence and mortality in 60 selected countries by cancer registry data integrity in 2020 were estimated from the GLOBOCAN database, and their association with the human development index (HDI) was further evaluated. Trends of age-standardized rates of incidence and mortality in 60 countries from 2000 through 2019 were evaluated by joinpoint regression analysis using data of Global Burden of Disease 2019. The association between potential behavioral, metabolic, and socioeconomic risk factor exposure at the nation level retrieved from the World Bank and Global Health Observatory and the incidence and mortality of FBC were evaluated by multivariate linear regression.Results::FBC incidence and mortality varied greatly in the 60 included countries. Higher incidence and mo

作者：Luo Chenyu；Li Na；Lu Bin；Cai Jie；Lu Ming；Zhang Yuhan；Chen Hongda；Dai Min

来源：中华医学杂志英文版 2022 年 135卷 1期