Background::Hepatectomy for hepatocellular carcinoma (HCC) beyond the Milan criteria is shown to be beneficial. However, a high rate of post-operative HCC recurrence hinders the long-term survival of the patients. This study aimed to investigate and compare the impacts of tenofovir (TDF) and entecavir (ETV) on the recurrence of hepatitis B viral (HBV)-related HCC beyond the Milan criteria.Methods::Data pertaining to 1532 patients who underwent hepatectomy and received antiviral therapy between January 2014 and January 2019 were collected from five centers. Recurrence-free survival (RFS) analysis was performed using the Kaplan-Meier method. Cox proportional hazards regression analysis was performed to determine prognostic factors for HCC recurrence.Results::The analysis incorporates 595 HBV-related HCC patients. The overall 5-year RFS was 21.3

作者：Shen Junyi；Qi Weili；Dai Junlong；Leng Shusheng；Jiang Kangyi；Zhang Yu；Ran Shun；Li Chuan；Wen Tianfu

来源：中华医学杂志英文版 2022 年 135卷 3期