Purpose::Traumatic hemorrhagic shock is a life-threatening event worldwide. Severe brain trauma accompanying femoral fractures can trigger inflammatory responses in the body and increase preinflammatory cytokines such as TNF-α, IL-1. The primary treatment in these cases is hydration with crystalloids, which has both benefits and complications. The purpose of this study was to investigate the effects of fluid therapy on the hemodynamics, coagulation profiles, and blood gases in such patients.Methods::In this cross-sectional study, patients were divided into two groups: femoral fracture group and non-femoral group. The hemodynamic status, coagulation profile, and blood gases of patients in both groups were evaluated upon arrival at the hospital and again 2 h later. Data were analyzed by t-test and ANOVA with repeated data and paired samples t-test. Results::A total of 681 trauma patients (605 men and 76 women) participated in this study, including 69 (86.3

作者：Paydar Shahram；Akerdi Ali Taheri；Nikseresht Sadra；Abdolrahimzadeh-Fard Hossein；Shayan Leila；Ghahramani Zahra；Bolandparvaz Shahram；Abbasi Hamid Reza

来源：中华创伤杂志英文版 2021 年 24卷 1期