CXCL12, also known as SDF-1, is the single natural ligand for chemokine receptors CXCR4 and CXCR7. CXCL12 has angiogenic properties in normal endothelial tissue and is involved in the out...
来源:《Recent patents on anti-cancer drug discovery》 2012 年 7卷 3期
Kertesz et al. (Nature Genetics 2008) described PITA, a miRNA target prediction algorithm based on hybridization energy and site accessibility. In this note, we used a population genomics...
MicroRNAs (miRNA) have potential as diagnostic and prognostic biomarkers and as therapeutic targets in cancer. We sought to establish the relationship between miRNA expression and clinico...
来源:《Clinical cancer research : an official journal of the American Association for Cancer Research》 2012 年 18卷 2期
MicroRNAs are increasingly important in the study of cancer because of their ability to down regulate the expression of tumor suppressors and promote tumorigenesis. Here, miR-221, which i...
来源:《International journal of clinical and experimental medicine》 2015 年 8卷 2期
Black carbon (BC) is a marker of traffic pollution that has been associated with blood pressure (BP), but findings have been inconsistent. MicroRNAs (miRNAs) are emerging as key regulator...
来源:《Environmental health perspectives》 2010 年 118卷 7期
In order to define new prognostic subgroups in patients with glioblastoma a miRNA screen ( 1000 miRNAs) from paraffin tissues followed by a bio-mathematical analysis was performed.35 glio...
Many studies have reported several transcriptionally deregulated microRNAs (miRNAs) in papillary thyroid cancer (PTC) tissue in comparison with benign thyroid nodules and normal thyroid t...
来源:《World journal of surgical oncology》 2017 年 15卷 1期
Cell-free circulating microRNAs (miRNAs) in the blood are good diagnostic biomarker candidates for various physiopathological conditions, including cancer, neurodegeneration, diabetes and...
To study different imaging criteria for prediction of lymph node metastases (Stage III disease) in colon cancer using CT.In a retrospective setting, 483 consecutive patients with histolog...
来源:《Cancer imaging : the official publication of the International Cancer Imaging Society》 2017 年 17卷 1期