The intravascular ultrasound elasticity-palpography technique revisited: a reliable tool for the in vivo detection of vulnerable coronary atherosclerotic plaques.-临床诊疗知识库

The intravascular ultrasound elasticity-palpography technique revisited: a reliable tool for the in vivo detection of vulnerable coronary atherosclerotic plaques.

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作者：

Flavien, Deleaval；Adeline, Bouvier；Gérard, Finet；Guy, Cloutier；Saami K, Yazdani；Simon, Le Floc'h；Patrick, Clarysse；Roderic I, Pettigrew；Jacques, Ohayon

来源：

Ultrasound in medicine & biology 2013 年 39卷 8期

标签：

Atherosclerosis Coronary disease Elastography Inverse problem Vulnerable plaques

Critical to the detection of vulnerable plaques (VPs) is quantification of their mechanical properties. On the basis of intravascular ultrasound (IVUS) echograms and strain images, E. I. Céspedes, C. L. de Korte CL and A. F. van der Steen (Ultrasound Med Biol 2000;26:385-396) proposed an elasticity-palpography technique (E-PT) to estimate the apparent stress-strain modulus palpogram of the thick endoluminal layer of the arterial wall. However, this approach suffers from major limitations because it was developed for homogeneous, circular and concentric VPs. The present study was therefore designed to improve the E-PT by considering the anatomic shape of the VP. This improved E-PT was successfully applied to six coronary lesions of patients imaged in vivo with IVUS. Our results indicate that the mean relative error of the stress-strain modulus decreased from 61.02 ± 9.01

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