This study sought to determine whether a simple score combining indexes of right ventricular (RV) function and right atrial (RA) size would offer good discrimination of outcome in patients with pulmonary arterial hypertension (PAH).Identifying a simple score of outcome could simplify risk stratification of patients with PAH and potentially lead to improved tailored monitoring or therapy.We recruited patients from both Stanford University (derivation cohort) and VU University Medical Center (validation cohort). The composite endpoint for the study was death or lung transplantation. A Cox proportional hazard with bootstrap CI adjustment model was used to determine independent correlates of death or transplantation. A predictive score was developed using the beta coefficients of the multivariable models.For the derivation cohort (n = 95), the majority of patients were female (79

作者：Fran?ois, Haddad；Onno A, Spruijt；Andre Y, Denault；Olaf, Mercier；Nathan, Brunner；David, Furman；Elie, Fadel；Harm J, Bogaard；Ingela, Schnittger；Bojan, Vrtovec；Joseph C, Wu；Vinicio, de Jesus Perez；Anton, Vonk-Noordegraaf；Roham T, Zamanian

来源：JACC. Cardiovascular imaging 2015 年 8卷 6期