Growing attention has been addressed to the cardiovascular effects of vitamin D, in order to prevent the vascular wall degeneration and the progression of atherosclerosis. Diabetes mellitus is an established risk factor for coronary artery disease, where the enhanced pro-inflammatory and pro-thrombotic status could render even more important the athero-protective effects of vitamin D. Therefore, we aimed to evaluate the impact of diabetes on vitamin D levels and its relationship with the extent of CAD.Consecutive patients undergoing non urgent coronary angiography were included. Admission samples were collected for vitamin D levels assessment. Significant coronary artery disease was defined as at least 1 vessel stenosis >50
作者:Matteo, Nardin;Monica, Verdoia;Alon, Schaffer;Lucia, Barbieri;Paolo, Marino;Giuseppe, De Luca
来源:Atherosclerosis 2016 年 250卷