White matter hyperintensity (WMH) volume and covert brain infarcts are highly prevalent in older adults and are often asymptomatic. We compared the impact of WMH volume and brain infarcts on risk of clinical stroke and dementia in older adults in the population.Participants were 1677 individuals aged ≥65 years from the 3-City Dijon study, who were free of stroke and dementia at baseline, followed-up for ≤12 years.Both lesion types were comparably associated with an increased risk of stroke (adjusted hazard ratio, 1.72; 95
作者:Sara, Kaffashian;A?cha, Soumaré;Yi-Cheng, Zhu;Bernard, Mazoyer;Stéphanie, Debette;Christophe, Tzourio
来源:Stroke 2016 年 47卷 11期