Epalrestat is clinically applied for the management of diabetic peripheral neuropathy, yet its pharmacokinetic properties are not well understood. In this study, a rapid and sensitive LC-MS/MS method was established for assaying epalrestat in bio-samples of mice. The method was validated and it showed a good linearity over the range of 2-5000ng/mL, a precision of less than 12.3
作者：Jingqiu, Huang；Runbin, Sun；Siqi, Feng；Jun, He；Fei, Fei；Haoxue, Gao；Yuqing, Zhao；Yue, Zhang；Huilin, Gu；Jiye, Aa；Guangji, Wang
来源：Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2017 年 1055-1056卷
