Prevalence, risk factors and consequences of cerebral small vessel diseases: data from three Asian countries.-临床诊疗知识库

Prevalence, risk factors and consequences of cerebral small vessel diseases: data from three Asian countries.

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作者：

Saima, Hilal；Vincent, Mok；Young Chul, Youn；Adrian, Wong；Mohammad Kamran, Ikram；Christopher Li-Hsian, Chen

来源：

Journal of neurology, neurosurgery, and psychiatry 2017 年 88卷 8期

标签：

Asians Cerebral Small Vessel Disease Cognitive impairment Magnetic Resonance Imaging

Cerebral small vessel disease (SVD) has been suggested to be more common in Asians compared with Caucasians. However, data from population-based studies in Asia are lacking. We report on the prevalence, risk factors and consequences of SVD from contemporary studies in three Asian countries using 3-Tesla MRI for the evaluation of SVD.Clinical, cognitive and 3-Tesla brain MRI assessments were performed among participants of three studies from Singapore, Hong Kong and Korea. SVD markers include white matter hyperintensities (WMHs) using the modified Fazekas scale, lacunes and microbleeds. Cognition was assessed using the Mini Mental Status Examination (MMSE) and Montreal Cognitive Assessment (MoCA). Adjustments were made for age, sex and cardiovascular risk factors.A total of 1797 subjects were available for analysis (mean age: 70.1±6.3 years and 57

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