Long non-coding RNAs ( lncRNAs ) are a group of RNAs , which are longer than 200 nucleotides without containing functional open reading frame and cannot encode protein .The study of lncRNA will help to understand the multi-level expression regulatory network of the body , and is expected to provide the basis of prediction , diagnosis and treatment of complex diseases .Although the functions and mechanism of lncRNA remain unclear , some studies indicate that lncRNA is involved in the development of diabetes mellitus , and those lncRNAs may be new diagnostic markers and therapeutic targets .
作者：韩泽平；何金花；黎毓光
来源：中国病理生理杂志 2014 年 4期
