Objective: To explore the characteristics of bone mineral density (BMD) and treatment in Chinese patients with complete androgen insensitivity syndrome (CAIS).Methods: Fourteen cases of CAIS were studied retrospectively through analyzing and comparing BMD of pre-and post-gonadectomy with healthy Chinese men and women. BMD at the lumbar spine and the femur were measured by dual energy X-ray absorptiometry (DXA). Results: There were 10 cases of CAIS having pre-gonadectomy DXA, in which 6 cases had very significantly reduced lumbar 2-4 BMD [(0.92±0.08) g/cm2] comparing with both healthy men and women (P＜0.01), 5 cases had significantly reduced femur neck BMD [(0.89±0.12) g/cm2] comparing with healthy men (P＜0.05). There were 7 cases having 12 post-gonadectomy DXA, in which all lumbar 2-4 BMD [(0.95±0.06) g/cm2] were reduced very significantly comparing with both healthy men and women (P＜0.01), femur neck BMD [(0.91±0.08) g/cm2] were also reduced significantly comparing with healthy men (P＜0.01) and wom

来源：生殖医学杂志 2005 年 14卷 z1期