Backgrounds::Azithromycin mass drug administration (MDA) is a key part of the strategy for controlling trachoma. This systematic review aimed to comprehensively summarize the present studies of azithromycin MDA on trachoma; provide an overview of the impact of azithromycin MDA on trachoma in different districts; and explore the possible methods to enhance the effectiveness of azithromycin MDA in hyperendemic districts.Methods::PubMed, Embase, the Cochrane Central Register of Controlled Trials, Web of Science, and ClinicalTrials.gov were searched up to February 2021 with no language restriction. Studies reporting the effect of azithromycin MDA on trachoma were included. Mathematical modeling studies, animal studies, case reports, and reviews were excluded. The trachomatous inflammation-follicular (TF) <5.0

作者：Tao Xiong；Yan Yue；Wen-Xing Li；Imti Choonara；Shamim Qazi；Hong-Ju Chen；Jun Tang；Jing Shi；Hua Wang；Li-Nan Zeng；Bin Xia；Li-Na Qiao；Yi Qu；De-Zhi Mu

来源：中华医学杂志英文版 2021 年 134卷 24期